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tumor ccl2 levels  (R&D Systems)


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    R&D Systems tumor ccl2 levels
    ( A ) Expression levels of Il1a , <t>ccl2</t> , and ccl3 in sorted populations of EGFP + B16F10 cells, EGFP – VE-cadherin + endothelial cells, and EGFP – CD45 + hematopoietic cells as measured by qPCR. The results are expressed as the relative mean ± SEM of Gapdh mRNA levels ( n = 3 experiments). ( B and C ) Representative images (scale bar: 50 μm) ( B ) showing CD45 + cell infiltrates (green, indicated by arrowheads) in control and shSHP2-silenced B16F10 tumors and quantification ( C ). Gray circles: percentage of CD45 + area/unit of tumor area; colored dots: mean/tumor ( n = 5/group). ** P < 0.01, by 2-tailed Student’s t test. ( D and E ) Representative images (scale bar: 50 μm) ( D ) showing F4/80 (green) macrophage infiltration in control and shSHP2-silenced B16F10 tumors (indicated by arrowheads) and quantification ( E ). Gray circles: percentage of F4/80 + area/unit of tumor area; colored dots: mean/tumor ( n = 5/group). ** P < 0.01, by 2-tailed Student’s t test. ( F ) Proposed model of downstream effects from SHP2 silencing in B16F10 melanoma cells leading to the formation of vascular tumor islands and surrounding tumor cell death. Results in panels A , C and E are presented as means± SEM.
    Tumor Ccl2 Levels, supplied by R&D Systems, used in various techniques. Bioz Stars score: 96/100, based on 217 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/tumor+ccl2+levels/pmc12077907-208-0-12?v=R%26D+Systems
    Average 96 stars, based on 217 article reviews
    tumor ccl2 levels - by Bioz Stars, 2026-08
    96/100 stars

    Images

    1) Product Images from "Induced clustering of SHP2-depleted tumor cells in vascular islands restores sensitivity to MEK/ERK inhibition"

    Article Title: Induced clustering of SHP2-depleted tumor cells in vascular islands restores sensitivity to MEK/ERK inhibition

    Journal: The Journal of Clinical Investigation

    doi: 10.1172/JCI181609

    ( A ) Expression levels of Il1a , ccl2 , and ccl3 in sorted populations of EGFP + B16F10 cells, EGFP – VE-cadherin + endothelial cells, and EGFP – CD45 + hematopoietic cells as measured by qPCR. The results are expressed as the relative mean ± SEM of Gapdh mRNA levels ( n = 3 experiments). ( B and C ) Representative images (scale bar: 50 μm) ( B ) showing CD45 + cell infiltrates (green, indicated by arrowheads) in control and shSHP2-silenced B16F10 tumors and quantification ( C ). Gray circles: percentage of CD45 + area/unit of tumor area; colored dots: mean/tumor ( n = 5/group). ** P < 0.01, by 2-tailed Student’s t test. ( D and E ) Representative images (scale bar: 50 μm) ( D ) showing F4/80 (green) macrophage infiltration in control and shSHP2-silenced B16F10 tumors (indicated by arrowheads) and quantification ( E ). Gray circles: percentage of F4/80 + area/unit of tumor area; colored dots: mean/tumor ( n = 5/group). ** P < 0.01, by 2-tailed Student’s t test. ( F ) Proposed model of downstream effects from SHP2 silencing in B16F10 melanoma cells leading to the formation of vascular tumor islands and surrounding tumor cell death. Results in panels A , C and E are presented as means± SEM.
    Figure Legend Snippet: ( A ) Expression levels of Il1a , ccl2 , and ccl3 in sorted populations of EGFP + B16F10 cells, EGFP – VE-cadherin + endothelial cells, and EGFP – CD45 + hematopoietic cells as measured by qPCR. The results are expressed as the relative mean ± SEM of Gapdh mRNA levels ( n = 3 experiments). ( B and C ) Representative images (scale bar: 50 μm) ( B ) showing CD45 + cell infiltrates (green, indicated by arrowheads) in control and shSHP2-silenced B16F10 tumors and quantification ( C ). Gray circles: percentage of CD45 + area/unit of tumor area; colored dots: mean/tumor ( n = 5/group). ** P < 0.01, by 2-tailed Student’s t test. ( D and E ) Representative images (scale bar: 50 μm) ( D ) showing F4/80 (green) macrophage infiltration in control and shSHP2-silenced B16F10 tumors (indicated by arrowheads) and quantification ( E ). Gray circles: percentage of F4/80 + area/unit of tumor area; colored dots: mean/tumor ( n = 5/group). ** P < 0.01, by 2-tailed Student’s t test. ( F ) Proposed model of downstream effects from SHP2 silencing in B16F10 melanoma cells leading to the formation of vascular tumor islands and surrounding tumor cell death. Results in panels A , C and E are presented as means± SEM.

    Techniques Used: Expressing, Control



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    tumor ccl2 levels  (R&D Systems)
    96
    R&D Systems tumor ccl2 levels
    ( A ) Expression levels of Il1a , <t>ccl2</t> , and ccl3 in sorted populations of EGFP + B16F10 cells, EGFP – VE-cadherin + endothelial cells, and EGFP – CD45 + hematopoietic cells as measured by qPCR. The results are expressed as the relative mean ± SEM of Gapdh mRNA levels ( n = 3 experiments). ( B and C ) Representative images (scale bar: 50 μm) ( B ) showing CD45 + cell infiltrates (green, indicated by arrowheads) in control and shSHP2-silenced B16F10 tumors and quantification ( C ). Gray circles: percentage of CD45 + area/unit of tumor area; colored dots: mean/tumor ( n = 5/group). ** P < 0.01, by 2-tailed Student’s t test. ( D and E ) Representative images (scale bar: 50 μm) ( D ) showing F4/80 (green) macrophage infiltration in control and shSHP2-silenced B16F10 tumors (indicated by arrowheads) and quantification ( E ). Gray circles: percentage of F4/80 + area/unit of tumor area; colored dots: mean/tumor ( n = 5/group). ** P < 0.01, by 2-tailed Student’s t test. ( F ) Proposed model of downstream effects from SHP2 silencing in B16F10 melanoma cells leading to the formation of vascular tumor islands and surrounding tumor cell death. Results in panels A , C and E are presented as means± SEM.
    Tumor Ccl2 Levels, supplied by R&D Systems, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/tumor+ccl2+levels/pmc12077907-208-0-12?v=R%26D+Systems
    Average 96 stars, based on 1 article reviews
    tumor ccl2 levels - by Bioz Stars, 2026-08
    96/100 stars
    		  Buy from Supplier

    Image Search Results


    ( A ) Expression levels of Il1a , ccl2 , and ccl3 in sorted populations of EGFP + B16F10 cells, EGFP – VE-cadherin + endothelial cells, and EGFP – CD45 + hematopoietic cells as measured by qPCR. The results are expressed as the relative mean ± SEM of Gapdh mRNA levels ( n = 3 experiments). ( B and C ) Representative images (scale bar: 50 μm) ( B ) showing CD45 + cell infiltrates (green, indicated by arrowheads) in control and shSHP2-silenced B16F10 tumors and quantification ( C ). Gray circles: percentage of CD45 + area/unit of tumor area; colored dots: mean/tumor ( n = 5/group). ** P < 0.01, by 2-tailed Student’s t test. ( D and E ) Representative images (scale bar: 50 μm) ( D ) showing F4/80 (green) macrophage infiltration in control and shSHP2-silenced B16F10 tumors (indicated by arrowheads) and quantification ( E ). Gray circles: percentage of F4/80 + area/unit of tumor area; colored dots: mean/tumor ( n = 5/group). ** P < 0.01, by 2-tailed Student’s t test. ( F ) Proposed model of downstream effects from SHP2 silencing in B16F10 melanoma cells leading to the formation of vascular tumor islands and surrounding tumor cell death. Results in panels A , C and E are presented as means± SEM.

    Journal: The Journal of Clinical Investigation

    Article Title: Induced clustering of SHP2-depleted tumor cells in vascular islands restores sensitivity to MEK/ERK inhibition

    doi: 10.1172/JCI181609

    Figure Lengend Snippet: ( A ) Expression levels of Il1a , ccl2 , and ccl3 in sorted populations of EGFP + B16F10 cells, EGFP – VE-cadherin + endothelial cells, and EGFP – CD45 + hematopoietic cells as measured by qPCR. The results are expressed as the relative mean ± SEM of Gapdh mRNA levels ( n = 3 experiments). ( B and C ) Representative images (scale bar: 50 μm) ( B ) showing CD45 + cell infiltrates (green, indicated by arrowheads) in control and shSHP2-silenced B16F10 tumors and quantification ( C ). Gray circles: percentage of CD45 + area/unit of tumor area; colored dots: mean/tumor ( n = 5/group). ** P < 0.01, by 2-tailed Student’s t test. ( D and E ) Representative images (scale bar: 50 μm) ( D ) showing F4/80 (green) macrophage infiltration in control and shSHP2-silenced B16F10 tumors (indicated by arrowheads) and quantification ( E ). Gray circles: percentage of F4/80 + area/unit of tumor area; colored dots: mean/tumor ( n = 5/group). ** P < 0.01, by 2-tailed Student’s t test. ( F ) Proposed model of downstream effects from SHP2 silencing in B16F10 melanoma cells leading to the formation of vascular tumor islands and surrounding tumor cell death. Results in panels A , C and E are presented as means± SEM.

    Article Snippet: Tumor CCL2 levels were measured with the Mouse CCL2 DuoSet ELISA kit (R&D Systems, mLMJE00B), and the colorimetric reaction was measured at 450 nm using a microplate reader (Imgen Technologies, BMG LABTECH).

    Techniques: Expressing, Control